A long-term follow-up study on effect of chronic tonsillitis with mesangial proliferative glomerulonephritis after tonsillectomy
10.3760/cma.j.issn.1674-2907.2015.12.003
- VernacularTitle:扁桃体切除术治疗慢性系膜增生性肾小球肾炎疗效的远期随访研究
- Author:
Xin SHAN
1
;
Dandan LIU
Author Information
1. 100853 北京，解放军总医院南楼保健科
- Keywords:
Glomerulonephritis,mesangial proliferation;
Tonsillectomy;
Follow-up study
- From:
Chinese Journal of Modern Nursing
2015;(12):1372-1375
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the curative effect of chronic tonsillitis with primary mesangial proliferative glomerulonephritis after tonsillectomy by follow-up. Methods We retrospect to analyze 67 patients with definite diagnosis of mesangial proliferative glomerulonephritis and complete data in hospital during January 2009 to December 2011. According to whether they allowed to have tonsillectomy, we divided them into experimental group ( 49 cases, accepted tonsillectomy ) and control group ( 18 cases, do not accepted tonsillectomy) . All patients in two groups underwent routine care of nephritis during follow-up. We compared and analyzed the general information, precursory symptom, the process of disease, clinical symptom, and 24 h urine protein amount and 1 h urine red cell count before treatment and 0. 5 month, 1 month, 6 month, 1 year and 3 years after treatment between two groups. The software of SPSS15. 0 had been used for statistical analysis. Results The amount of 24 h urine protein and 1 h urine red cell had no statistical significance before treatment, 0. 5 month after treatment between two groups (P>0. 05);24 h urine protein amounts were (0. 89 ± 0. 38), (0. 59 ± 0. 23), (0. 41 ± 0. 15), (0. 38 ± 0. 17) g at 1 month, 6 months, 1 year, 3 years after treatment lower than those of the control group (t=5. 711,8. 563,10. 282,10. 488,respectively; P<0. 001); the amounts of urine red cell were statistically significant at 1 month, 6 months, 1 year, 3 years after treatment between two groups (P<0. 001). The total curative effect in the experiment group was higher than that of the control group (Z=2. 316,P=0. 024);the further improvement rate of experimental group was better than that of the control group after 1 year′s treatment, but it represented an opposite trend between two group after 3 years′ treatment (Z=5. 832,P=0. 002). Conclusions The three-year follow-up results confirms that tonsillectomy could delay the process of glomerulonephritis and might benefit long-term prognosis and the existence of kidney, but we should consider the contraindications and adapted symptom, and utilized tonsillectomy at the early stage of disease with stable general condition of health.
