Research progress in protective antibodies against yellow fever virus

VernacularTitle:黄热病毒保护性抗体研究进展
Author: Xingxing SUO ^{1
,

2} ; Hang CHI ; Yongqiong DENG ; Xiaodong HAN
Author Information

1. 内蒙古农业大学生命科学学院,呼和浩特 010011
2. 军事科学院军事医学研究院,病原微生物生物安全全国重点实验室,北京 100071
Keywords: yellow fever virus; envelope protein; neutralizing antibody
From: Military Medical Sciences 2024;48(8):636-640
CountryChina
Language:Chinese
Abstract: Yellow fever virus(YFV)is one of the most important mosquito-borne flaviviruses in the world,causing about 200,000 infections and 30,000 deaths each year,with serious impacts on human health and economic development.Currently,there are no approved specific anti-viral drugs for YFV infection.On the other hand,antibody drugs are safe,highly targeted and effective,making them one of the most effective means of prevention and treatment of viral infectious diseases.This review summarizes the characteristics of YFV and the recent advances in the development of protective antibodies against YFV,and predict the priorities of future research and development of protective antibodies,which may offer a new line of thought for subsequent development of yellow fever virus-specific drugs.