Progress in the application of absolute ethanol in interventional embolization treatment of peripheral arteriovenous malformations
10.3969/j.issn.1008-794X.2024.11.018
- VernacularTitle:无水乙醇在外周动静脉畸形栓塞治疗中的应用进展
- Author:
Qianyun HAN
1
;
Yuchen SHEN
;
Deming WANG
;
Lixin SU
;
Xiao LI
;
Xindong FAN
Author Information
1. 200011 上海 上海交通大学医学院附属第九人民医院介入科
- Keywords:
arteriovenous malformation;
angiography;
embolization therapy;
sclerotherapy;
ethanol
- From:
Journal of Interventional Radiology
2024;33(11):1244-1252
- CountryChina
- Language:Chinese
-
Abstract:
Arteriovenous malformations(AVMs)are a kind of high-flow vascular malformation.AVMs can be classified in many ways,including histo-embryological classification,hemodynamic classification,etc.At present,the two mainstream classification systems used to guide the embolization treatment of peripheral AVMs are proposed by Cho and Yakes respectively based on the angiographic morphology of the lesions.Interventional embolization is the first-line treatment for AVMs.Among the many embolization agents,absolute ethanol is a permanent liquid embolization agent.Absolute ethanol can directly destroy the vascular endothelial cells to achieve a good curative efficacy,therefore,it has been wildly used in the treatment of peripheral AVMs.Yakes classification combines the angiographic classification with absolute ethanol embolization therapy.During absolute ethanol treatment,close attention should be paid to the occurrence of complications such as elevated pulmonary artery pressure.Although there are challenges remaining in the treatment of AVMs,the rapid development of molecular genetics has made targeted drug adjunctive treatment for AVMs possible.Perhaps,the novel therapeutic mode of combination use of traditional therapy targeted drug may be able to make a breakthrough in the treatment of AVMs.
