Post-embolization syndrome occurring after transhepatic arterial chemoembolization:analysis of its related factors
10.3969/j.issn.1008-794X.2024.11.014
- VernacularTitle:肝动脉化疗栓塞术发生栓塞综合征的相关因素分析
- Author:
Mingzhu GAO
1
;
Kewu HE
;
Guangjing GUO
;
Lili LI
Author Information
1. 230001 安徽合肥 合肥市第一人民医院介入血管外科
- Keywords:
hepatocellular carcinoma;
transhepatic arterial chemoembolization;
complication;
post-embolization syndrome;
risk factor;
perioperative intervention strategy
- From:
Journal of Interventional Radiology
2024;33(11):1225-1228
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the factors influencing the occurrence of post-embolization syndrome(PES)after transhepatic arterial chemoembolization(TACE).Methods A total of 107 patients with hepatocellular carcinoma(HCC),who received TACE treatment at authors'hospital between February 2021 and March 2023,were included in the study.Among them,56 patients developed PES(PES group)and 51 patients did not develop PES(non-PES group).The demographic data,medical history,pathological findings,laboratory indicators and operation-related materials were compared between the two groups,and the risk factors for PES were analyzed.Results There were statistically significant differences in tumor diameter,albumin(ALB)level,preoperative physical condition(ECOG)score,type of embolization agent,drug-loaded microspheres,number of microspheres,and dosage of loaded drug between the two groups(all P＜0.05).Multivariate Logistic analysis revealed that drug-loaded microspheres,number of microspheres,and dosage of loaded drug were the independent risk factors for PES occurring after TACE(all P＜0.05).Conclusion HCC patients treated with TACE using drug-loaded microspheres,large amount of microspheres and high dosage of loaded drug have a higher risk of PES occurring after TACE.For patients having the above risk factors,the formulation of corresponding perioperative intervention strategies is necessary so as to avoid the occurrence of PES and to improve the safety of TACE.
