Correlation between the growth speed of cerebral infarction and the symptomatic intracranial hemorrhage occurring in patients with acute anterior circulation large vessel occlusion after mechanical thrombectomy
10.3969/j.issn.1008-794X.2024.11.003
- VernacularTitle:脑梗死进展速度与急性前循环大血管闭塞患者机械取栓术后发生症状性颅内出血相关性研究
- Author:
Xusen YANG
1
;
Peicheng LI
;
Long CHEN
;
Bo LI
;
Yizhi LIU
;
Chen YUAN
;
Wanci LI
;
Yun DING
Author Information
1. 215006 江苏苏州 苏州大学附属第一医院介入科
- Keywords:
mechanical thrombectomy;
acute ischemic stroke;
growth speed of cerebral infarction;
symptomatic intracranial hemorrhage
- From:
Journal of Interventional Radiology
2024;33(11):1170-1174
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the impact of the growth speed of cerebral infarction on the occurrence of symptomatic intracranial hemorrhage(sICH)in patients with acute anterior circulation ischemic stroke after mechanical thrombectomy.Methods The clinical data of patients with acute ischemic stroke(AIS),who received mechanical thrombectomy at the First Affiliated Hospital of Soochow University of China from June 2016 to December 2022,were retrospectively analyzed.After thrombectomy,the patients were divided into sICH group and non-sICH group according to Heidelberg criteria.The clinical data and imaging findings were compared between the two groups.Multivariate logistic regression analysis was used to identify the independent risk factors for sICH after thrombectomy,and the area under the receiver operating characteristic curve(AUC)was used to evaluate the efficacy of the growth speed of cerebral infarction in predicting sICH.Results A total of 218 patients were enrolled in this study,sICH group had 23 patients and non-sICH group had 195 patients.The differences in NIHSS score,collateral circulation status,core infarction volume,and growth speed of cerebral infarction between the two groups were statistically significant(all P＜0.05).Multivariate logistic regression analysis showed that rapid growth speed of cerebral infarction was an independent risk factor for sICH occurring after mechanical thrombectomy.For predicting sICH,the sensitivity and specificity of the growth speed of cerebral infarction were 78.3％and 69.7％respectively,with an AUC of 0.751 and a predicted value of 7.6 mL/h.Conclusion The rapid growth speed of cerebral infarction is a predictive factor for sICH occurring after mechanical thrombectomy in patients with acute anterior circulation ischemic stroke.The risk of sICH becomes higher after mechanical thrombectomy when the growth speed of cerebral infarction is faster than 7.6 mL/h.
