Clinical application of CT angiography-derived fractional flow reserve in evaluating the risk stratification of coronary artery stenosis and the myocardial function
10.3969/j.issn.1008-794X.2024.09.005
- VernacularTitle:CT血流储备分数对冠状动脉狭窄危险分层及功能评价的临床初探
- Author:
Yongguang GAO
1
;
Ping XIA
;
Yibing SHI
;
Yu LI
;
Jinyao ZHANG
;
Yufei FU
;
Yayong HUANG
;
Yuanshun XU
;
Gutao LI
Author Information
1. 221000 江苏徐州 徐州市中心医院CT室
- Keywords:
tomography,X-ray computed;
coronary artery;
fractional flow reserve
- From:
Journal of Interventional Radiology
2024;33(9):956-960
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the clinical application of coronary CT angiography(CCTA)-derived fractional flow reserve(CT-FFR)in evaluating the risk stratification of the coronary artery stenosis and atherosclerotic plaque quantitative parameters.Methods A total of 122 patients,who received CCTA examination at the Xuzhou Municipal Central Hospital of China,were enrolled in this study.The patients were divided into non-ischemia group(CT-FFR＞0.8,n=66)and ischemia group(CT-FFR0.8,n=56).The characteristics of atherosclerotic plaque were compared between the two groups.Logistic regression analysis was used to analyze the correlation between plaque characteristics and ischemic lesions.Results There were 218 vessels having a CT-FFR＞0.8 and 174 vessels having a CT-FFR ≤0.8.Statistically significant differences in the total plaque volume,calcified plaque volume,plaque length,and stenosis ratio＞50％existed between the two groups(all P＜0.05).Logistic regression analysis indicated that the total plaque volume,calcified plaque volume,plaque length,and stenosis ratio＞50％were the risk factors for myocardial ischemia.Conclusion CT-FFR can be used for the risk stratification of coronary stenosis and atherosclerotic plaque characteristics,which can evaluate the local myocardial blood supply condition from the anatomical stenosis and functional level so as to optimize the diagnosis and treatment measures.
