Analysis of the factors influencing the pregnancy rate after fallopian tube recanalization and its nomogram model validation
10.3969/j.issn.1008-794X.2024.08.009
- VernacularTitle:输卵管再通术后妊娠率影响因素分析及列线图模型验证
- Author:
Shengpan JIANG
1
;
Shilin ZHENG
;
Xiaoqing GAO
;
Yiqing TAN
Author Information
1. 430074 湖北武汉 武汉市第三医院介入医学科
- Keywords:
fallopian tube recanalization;
infertility;
pregnancy rate;
prediction model;
nomogram
- From:
Journal of Interventional Radiology
2024;33(8):860-864
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the factors influencing the pregnancy rate after fallopian tube recanalization(FTR),and to construct and validate a nomogram prediction model.Methods The clinical data of a total of 322 female patients with tubal obstructive infertility,who received FTR at the Wuhan Municipal Third Hospital of China between January 2018 and December 2022,were retrospectively analyzed.According to whether the female patient had natural pregnancy or not within 12 months after FTR treatment,the female patients were divided into the pregnant group and the non-pregnant group.Logistic regression analysis was used to determine the independent factors influencing pregnancy.The female patients were randomly divided into training group and validation group at 1∶1 ratio.A nomogram model was constructed in the training group,and the predictive efficacy of the model was verified in the validation group by using receiver operating characteristic(ROC)curves,calibration curves and decision curve analysis(DCA).Results The natural pregnancy rate at one year after FTR was 45.34％(146/322).Age＞35 years,primary infertility,duration of infertility＞3 years,distal fallopian tube obstruction,and moderate to severe tubal lesion were the independent risk factors affecting the pregnancy rate after FTR(all P＜0.05).The constructed nomogram model had a good differentiation and calibration ability and it carried a high degree of clinical utility.Conclusion The nomogram model constructed in this study can effectively predict the risk of infertility within one year after FTR treatment,which is helpful for formulating the individualized therapeutic scheme for infertility female patients.
