Advances in interventional therapies for pancreatic cancer pain
10.3969/j.issn.1008-794X.2024.07.019
- VernacularTitle:胰腺癌性疼痛介入治疗的研究进展
- Author:
Wandi ZHANG
1
;
Xiaofu ZHANG
;
Baoshan WANG
;
Guojun HAO
;
Peiyong LI
;
Dongfeng SHEN
Author Information
1. 030000 山西太原 山西省中医药研究院,山西省中医院介入血管科
- Keywords:
pancreatic tumor;
cancer pain;
neural destruction;
125I particle implantation;
intrathecal drug infusion system;
patient-controlled analgesic pump technique
- From:
Journal of Interventional Radiology
2024;33(7):801-807
- CountryChina
- Language:Chinese
-
Abstract:
Clinically,pancreatic cancer is a highly aggressive tumor,and neurotropic growth is an important biological feature of pancreatic cancer.Nerve invasion brings great pain burden to patients,and it seriously affects the quality of life and the will to survive of patients.The"three-step analgesia principle"for the management of cancer pain proposed by World Health Organization(WHO)is a traditional therapeutic regimen for cancer pain.However,because of its obvious toxic side effects,poor efficacy,easy addiction,easy drug resistance,non-standard medication of clinical physicians,etc.,the"three-step analgesia principle"is unable to meet the needs of the patient's condition..In recent years,with the development of interventional technology and the development of extensive clinical trials,the interventional means,which is regarded as the"fourth step"of cancer pain management,has achieved great clinical effect,it includes various therapeutic methods and imaging-guided techniques such as neural destruction(denervation),125I particle implantation,patient-controlled analgesic pump technology,implantation of intrathecal drug infusion system,etc.,and clinical practice has proved that these techniques have significant clinical efficacy and they can provide a convenient,safe and effective treatment method for HCC patients.