CT-guided 125I seeds implantation for abdominal wall incision metastasis of gastrointestinal malignancies
10.3969/j.issn.1008-794X.2024.06.014
- VernacularTitle:CT引导下125I粒子植入治疗胃肠道恶性肿瘤腹壁切口转移
- Author:
Bai SUN
1
;
Hao WANG
;
Chao WANG
;
Weiguang QIANG
;
Ye YUAN
;
Hongbin SHI
Author Information
1. 213000 江苏常州 苏州大学附属第三医院
- Keywords:
incision metastasis;
gastrointestinal tumor;
125I seed;
effectiveness;
safety
- From:
Journal of Interventional Radiology
2024;33(6):655-658
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy and safety of CT-guided 125I seeds implantation for the treatment of abdominal wall incision metastasis of gastrointestinal malignancies.Methods The clinical data of 17 patients with abdominal wall incision metastasis of gastrointestinal malignancies(17 lesions in total),who received CT guided 125I seeds implantation at the Third Affiliated Hospital of Soochow University of China between January 2011 and December 2021,were collected.The treatment planning system was used to make preoperative planning for CT-guided 125I seeds implantation.Follow-up visit was performed once every 3 months to assess the local control rate,treatment-related adverse effects,and degree of pain relief.Results Successful CT-guided 125I seeds implantation was accomplished for the 17 lesions of gastrointestinal malignant tumor incision metastasis.A total of 372 125I seeds were implanted with an average of 21.9 seeds per lesion.The average prescription dose was 100 Gy per lesion.The average survival time was 9.8 months.CT scan performed at 3 months after first-time implantation showed that among the 17 lesions complete remission was obtained in 3,partial remission in 6,stable disease in 7 and progression in one,with a local control rate of 94.1％.The postoperative 6-month and 12-month local objective remission rates were 63.6％and 33.3％respectively,disease control rates were 100％and 50％respectively.Before treatment 8 patients had local pain,and 3 months after treatment pain relief was observed in 6 patients,and in 2 patients the NRS pain score was decreased by ≥ 2 points.No serious postoperative complications occurred.Conclusion For the treatment of abdominal wall incision metastasis of gastrointestinal metastasis,CT-guided 125I seeds implantation is clinically safe and effective.(J Intervent Radiol,2024,33:655-658)
