Interventional treatment of bronchopleural fistula:analysis of its efficacy and safety
10.3969/j.issn.1008-794X.2024.06.011
- VernacularTitle:支气管胸膜瘘介入治疗的有效性和安全性分析
- Author:
Yanchun LI
1
;
Xiaobing LI
;
Xiaolong DING
;
Meipan YIN
;
Yaozhen MA
;
Chunxia LI
;
Xinwei HAN
;
Gang WU
Author Information
1. 450052 河南洛阳 解放军联勤保障部队第九八九医院呼吸与危重症医学科
- Keywords:
lung cancer;
lobectomy;
bronchopleural fistula;
stent;
drainage;
interventional radiology
- From:
Journal of Interventional Radiology
2024;33(6):641-645
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy and safety of interventional therapy for bronchopleural fistula(BPF).Methods A total of 172 patients with confirmed BPF were treated with continuous negative pressure drainage(CNPD)and/or airway stent occlusion therapy.The clinical data were collected,and its effectiveness and safety were analyzed.Results In 5-7 days after interventional treatment,the pneumonia severity index(PSI)decreased significantly,and successful drainage was achieved in 166 patients(96.5％).One month after interventional therapy,the lung volume was remarkably increased.The median clinical healing time of interventional therapy was 9.0 months(95％CI=6.18-1 1.83).Multivariate analysis of the Cox proportional hazards model showed that the diagnosis time(HR=0.53,95％CI=0.38-0.74,P＜0.01)and fistula size(HR=0.74,95％CI=0.55-0.99,P=0.04)were significantly correlated with the clinical healing time.Conclusion For the treatment of BPF,CNPD and/or airway stent occlusion has several advantages such as accurate operation,minimally invasive,safe and effective.It can quickly improve the symptoms and quality of life,and prolong survival,therefore,it is worthy of clinical promotion and application.(J Intervent Radiol,2024,33:641-645)
