Ultrasound-guided microwave ablation for multifocal T1N0M0 papillary thyroid carcinoma:a feasibility study
10.3969/j.issn.1008-794X.2024.05.006
- VernacularTitle:超声引导下微波消融治疗多灶性T1N0M0甲状腺乳头状癌的可行性研究
- Author:
Meiqin GU
1
;
Jing XI
;
Zun LI
;
Feng QIAN
Author Information
1. 213000 江苏常州 江苏大学附属武进医院(徐州医科大学武进临床学院)超声科
- Keywords:
ultrasound;
microwave ablation;
thyroid papillary carcinoma;
maximum tumor diameter;
thyroid hormone
- From:
Journal of Interventional Radiology
2024;33(5):495-499
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the feasibility,safety,and effectiveness of ultrasound-guided microwave ablation in the treatment of multifocal T1N0M0 papillary thyroid carcinoma(PTC).Methods A total of 68 patients with multifocal T1N0M0(≤ 3 lesions)PTC,whose diagnosis was confirmed at authors'hospital from January 2019 to January 2022,were randomly included as the study subjects.The maximum diameter of tumor was ≤2 cm.Ultrasound-guided microwave ablation was carried out in all patients.The patients were followed up until April 2023,with a median time of 30 months.The follow-up examinations included conventional ultrasound,contrast-enhanced ultrasound,thyroid function,and necessary fine needle aspiration cytology(FNA).Results The 68 patients were divided into T1a group(n=52)and T1b group(n=16).The ablation time in Tib group was significantly longer than that in T1a group,and the maximum diameter of tumor in T1b group was significantly larger than that in T1a group,the differences were statistically significant(P＜0.05).All 68 patients successfully completed the surgery and were recovered at discharge with no obvious complications.Contrast-enhanced ultrasound imaging revealed that the ablated lymph nodes showed no enhancement.Post-ablation one-,3-and 6-month maximum diameters and volumes of the tumor were significantly larger than their pre-ablation values(P＜0.05).Post-ablation 12-,18-and 24-month maximum diameters and volumes of the tumor were gradually decreased(P＜0.05).No tumor progression or recurrence was observed during follow-up period.Thyroid function including thyroglobulin,total thyroxine,and thyrotropin,which were determined before ablation and at the last follow-up visit,showed no significant changes(P＞0.05).Conclusion For the treatment of T1N0M0 PTC,ultrasound-guided microwave ablation has excellent clinical feasibility,safety,and effectiveness.(J Intervent Radiol,2024,33:495-499)
