Sleep disorders and perioperative neurocognitive dysfunction
10.11855/j.issn.0577-7402.1265.2024.0612
- VernacularTitle:围手术期睡眠紊乱与神经认知功能障碍
- Author:
Chao-Chao ZHA
1
;
Shi-Lin LI
;
Ying-Wei WANG
;
Meng-Qiang LUO
Author Information
1. 复旦大学附属华山医院麻醉科,上海 200040
- Keywords:
sleep disorders;
general anesthesia;
perioperative neurocognitive disorder;
sleep modulation
- From:
Medical Journal of Chinese People's Liberation Army
2024;49(10):1099-1104
- CountryChina
- Language:Chinese
-
Abstract:
Perioperative neurocognitive disorder(PND)significantly threatens brain health,leading to prolonged hospitalization,increased patient mortality risk,and poor long-term prognosis.Sleep disorder may substantially elevate the risk of neurocognitive dysfunction.However,the specific role of sleep in PND development remains to be elucidated.In addition,controversy exists over whether interventions for perioperative sleep disorder can effectively prevent PND.Therefore,this review aims to explore the basic function and regulatory principles of sleep,the clinical characteristics of perioperative sleep disorder,its role and potential mechanisms in PND development.Furthermore,we also provide new evidence on the potential therapeutic strategies to modulate sleep disorder for PND management,to improve patient's neurocognitive prognosis and long-term outcomes.
