Nursing care of patients with acute radiation-induced oral mucositis treated with Shenmai Decoction plus Gene Time
10.3760/j.issn.1674-2907.2014.30.008
- VernacularTitle:参麦饮联合金因肽防治急性放射性口腔黏膜炎的护理
- Author:
Jingjing CAO
1
;
Huili XU
Author Information
1. 430345 武汉市中心医院北院肿瘤科
- Keywords:
Nursing;
Radioactive mucositis;
Gene Time ( Recombinant human epidermal growth factor);
Shenmai decoction
- From:
Chinese Journal of Modern Nursing
2014;20(30):3808-3811
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect and nursing care of Shenmai Decoction plus Gene Time ( recombinant human epidermal growth factor ) on the treatment of radiation oral mucositis .Methods Totals of 80 head-and-neck cancer patients receiving radiotherapy were randomly divided into treatment group ( n=40 ) and control group (n=40).The treatment group was treated with Shenmai Decoction in combination with Gene Time spraying on the irradiated oral mucosa after cleaned , while the control group was treated only with Gene Time.The course of treatment of both groups was 7 weeks.The total curative effect of two groups were observed and the nursing methods were summarized .Results As the increasing dose of radiotherapy , the incidence rates ofⅢ-degree and Ⅳ-degree oral mucositis were increased significantly in the two groups (15.0% vs 25.0%, 25.0%vs 40.0%;χ2 =13.08, 10.31, respectively;P<0.05).However, the incidence rate of Ⅲ-degree andⅣ-degree oral mucositis of treatment group was significantly lower than that of control group ( 15 .0% vs 25.0%, 25.0%vs 40.0%;χ2 =9.21,14.39, respectively;P<0.05).And total effective rate of treatment group was significantly better than that of control group ( 87.5% vs 85.0%; χ2 =0.105, P >0.05 ). Conclusions Shenmai Decoction plus Gene Time can reduce the incidence of radioactive oral mucositis and significantly enhance the curative effect .Nursing interventions can improve the rehabilitation of oral mucositis patients.
