The Natural History of Simple Renal Cysts in Adults.
- Author:
Byoung Kyu HAN
1
;
Doo Sang KIM
;
Nam Kyu LEE
Author Information
- Publication Type:Original Article
- Keywords: Kidney; Cyst; History
- MeSH: Adult*; Aging; Diagnosis; Follow-Up Studies; Humans; Kidney; Logistic Models; Natural History*
- From:Korean Journal of Urology 2006;47(1):80-84
- CountryRepublic of Korea
- Language:Korean
- Abstract: PURPOSE: Simple renal cysts are common in older patients and they are usually left untreated, yet only a few studies have been done on the natural history of simple renal cysts. We investigated the sequential changes in their size and number in 103 patients. MATERIALS AND METHODS: From January 1993 to August 2003, we followed 103 patients who were suffering with simple renal cysts. Their mean age was 55.8+/-18.72 years old (M:F=58:51). Using Abdominal USG and CT, the annual changes in renal cysts were analyzed through the follow-up period, and the mean follow-up period was 52.3+/-17.58 months. The values of the parameters were compared with using a 2-tailed Student's t-test, multivariate logistic regression analysis and the chi-square test. RESULTS: At the time of diagnosis, the mean number and size of simple renal cyst were 1.5+/-1.31 cysts per each kidney and 25.3+/-12.42mm, respectively. On the consecutive imaging study, the size of the renal cysts was increased 4.4+/-1.54mm per year. The average size increase was significantly greater in the individuals younger than 50 versus the patients 50 years or older (5.7+/-2.14mm/year vs 3.7+/-1.45mm/year, respectively). The multiple cysts showed a significantly larger size increase than did the single cysts (8.1+/-3.27mm/year vs 3.6+/-1.64mm/year, respectively). The size increase of the bilateral renal cysts was significantly larger than that of the unilateral renal cysts (5.6+/-1.48mm/year vs 4.1+/-1.02mm/year, respectively). No significant difference was observed for the average size increase with regard to gender or the initial cyst size. Only the number of cysts was a significant predictor of aggressiveness on the multivariate logistic regression analysis. CONCLUSIONS: The simple renal cysts progress in size and they appear to grow with aging. They seem to grow more rapidly in patients with a younger age, and for multiple and bilateral renal cysts.
