Progress on the role of N-acetyltransferase 10 in tumor development
10.16352/j.issn.1001-6325.2024.11.1589
- VernacularTitle:N-乙酰转移酶10在肿瘤发生发展中作用的研究进展
- Author:
Zhongjia GU
1
;
Siying LAI
;
Dunjin CHEN
;
Lili DU
Author Information
1. 广州医科大学附属第三医院 广州妇产科研究所 广东省产科重大疾病重点实验室广东省妇产疾病临床医学研究中心 粤港澳母胎医学高校联合实验室,广东 广州 510000
- Keywords:
N-acetyltransferase10;
N4-acetylcytidine;
tumor
- From:
Basic & Clinical Medicine
2024;44(11):1589-1593
- CountryChina
- Language:Chinese
-
Abstract:
N-acetyltransferase10(NAT10)is a protein widely expressed in a variety of tissues and cells.The high expression of NAT10 is closely related to tumor invasion,metastasis and drug resistance.The mechanism of NAT10 promoting tumor genesis and development involves the regulation of cell cycle,mRNA stability,translation efficien-cy and related pathways due to the changes in the expression or location of NAT10,thus affecting the occurrence,development and prognosis of tumors.
