Comparison of clinical outcomes between ABO-compatible and ABO-incompatible spousal donor kidney transplantation.
10.1016/j.krcp.2015.11.001
- Author:
Woo Yeong PARK
1
;
Seong Sik KANG
;
Sung Bae PARK
;
Ui Jun PARK
;
Hyong Tae KIM
;
Won Hyun CHO
;
Seungyeup HAN
Author Information
1. Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea. hansy@dsmc.or.kr
- Publication Type:Original Article
- Keywords:
Blood group incompatibility;
Kidney transplantation;
Spouses
- MeSH:
Blood Group Incompatibility;
Delayed Graft Function;
Follow-Up Studies;
Graft Rejection;
Graft Survival;
Humans;
Incidence;
Kidney Failure, Chronic;
Kidney Transplantation*;
Kidney*;
Retrospective Studies;
Spouses;
Tissue Donors*;
Transplants
- From:Kidney Research and Clinical Practice
2016;35(1):50-54
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: Kidney transplantation (KT) is the treatment of choice for end-stage renal disease patients. The spouse is a major donor in living KT. Clinical outcomes of spousal donor KT are not inferior to those of living related donor KT. In this study, we compared clinical outcomes between ABO-compatible (ABOc) and ABO-incompatible (ABOi) spousal donor KTs. METHODS: Thirty-two cases of spousal donor KT performed from January 2011 to August 2013 were analyzed retrospectively. Twenty-one ABOc KTs and 11 ABOi KTs were performed. We investigated patient survival, graft survival, acute rejection, graft function, and complications. RESULTS: During follow-up, patient and graft survival rates were 100% in both groups. There were no significant differences in the incidence of delayed graft function, acute rejection, and the change in graft function between the 2 groups. Medical and surgical complications were not significantly different between the groups. CONCLUSION: The clinical outcomes of ABOc and ABOi spousal donor KTs were equivalent. In ABOi KT, an emotionally motivated spousal donor KT may be a good alternative to the problem of the absolute shortage of kidney donations.
