Increased exercise is associated with reduced insulin resistance and cardiovascular risk factors in individuals with newly diagnosed diabetes
10.16352/j.issn.1001-6325.2024.07.0984
- VernacularTitle:新确诊糖尿病患者增加运动与降低胰岛素抵抗和心血管危险因素相关
- Author:
Mengya QI
1
;
Yuxiu LI
;
Jie YU
;
Huabing ZHANG
;
Lingling XU
;
Wei LI
;
Fan PING
Author Information
1. 中国医学科学院 北京协和医学院 北京协和医院 内分泌科 国家卫生健康委员会内分泌重点实验室,北京 100730
- Keywords:
exercise;
diabetes;
prediabetes;
insulin resistance;
neck circumference
- From:
Basic & Clinical Medicine
2024;44(7):984-988
- CountryChina
- Language:Chinese
-
Abstract:
Objective To identify the relationship between physical activity,insulin resistance and cardiovascular risk in individuals with different glucose tolerance status and to provide evidence for exercise intervention in people with different glucose tolerance status.Methods A total of 691 patients with different glucose metabolism status were recruited as subjects of the research.Spearman correlation analysis was used to study the relationship between exercise frequency and insulin resistance,insulin sensitivity,neck circumference(NC)and neck circumference height ratio(NHtR)in the subjects with different glucose metabolism status,the relationship between NC and insu-lin resistance and insulin sensitivity in different glucose metabolism groups.Results 171(62.9%)Subjects with diabetes were intervened by exercised every day.Spearman correlation analysis showed the correlation between exer-cise frequency and tri-glyceride triglyceride-glucose index(TyG index)(r=-0.120,P＜0.05)and NC(r=-0.168,P＜0.05)were negatively correlated.In subjects with diabetes,NC was positively correlated with triglyc-erides(TG)(r=-0.100,P＜0.05),homeostasis model assessment of insulin resistance(HOMA-R)(r=-0.163,P＜0.05),total cholesterol/high-density lipoprotein(TC/HDL-C)(r=-0.214,P＜0.05)and TyG index(r=-0.156,P＜0.05).Conclusions Increased frequency of exercise is associated with reduced NC,improved insulin resistance,and cardiovascular risk factors in subjects of our team with newly diagnosed diabetes.Exercise has no significant effect on insulin resistance of subjects with normal glucose tolerance and pre-diabetes.
