A case of hypopharyngeal amyloidosis by digestive endoscopy
10.11817/j.issn.1672-7347.2024.230483
- VernacularTitle:消化内镜检查发现下咽部淀粉样变性1例
- Author:
Ling HE
1
;
Wei SU
;
Lingli LI
;
Qiao ZHOU
;
Qiuling ZHAO
;
Hongping LI
Author Information
1. 遵义医科大学附属医院消化病医院,遵义医科大学附属医院消化内科,贵州遵义 563000
- Keywords:
hypopharynx;
amyloidosis;
digestive endoscopy
- From:
Journal of Central South University(Medical Sciences)
2024;49(4):643-648
- CountryChina
- Language:Chinese
-
Abstract:
Amyloidosis is a rare disease.This paper reports a case of localized secondary hypopharyngeal amyloidosis presenting with pulmonary tuberculosis as the initial symptom.The patient lacked specific clinical manifestations and primarily exhibited symptoms such as cough,sputum production,acid reflux,belching,and abdominal pain.Chest CT indicated bronchiectasis with infection and pulmonary tuberculosis.Digestive endoscopy revealed a white mucosal elevation at the right pyriform sinus of the hypopharynx.Pathological diagnosis confirmed amyloid deposits in the hypopharyngeal mucosal tissue.The patient tested positive for anti-amyloid A antibodies,Congo red staining(+),and periodate Schiff staining(+).Amyloidosis commonly affects the digestive system and may have various etiologies,often presenting with symptoms that overlap with other digestive system diseases,leading to frequent misdiagnosis and missed optimal treatment opportunities.The hypopharynx,a highly folded and narrow chamber that serves as a common passage for the digestive and respiratory tracts,can be effectively evaluated for amyloidosis using digestive endoscopy.
