Detection and clinical application of red blood cell survival

VernacularTitle:红细胞寿命的检测及其临床应用
Author: Shijin HUANG ¹ ; Jie YANG ; Yongbin YANG ; Jie LI
Author Information

1. 河北北方学院研究生院,河北张家口 075000
Keywords: red blood cell survival; carbon monoxide breath test; anemia; clinical application
From: Journal of Central South University(Medical Sciences) 2024;49(3):476-481
CountryChina
Language:Chinese
Abstract: There are 2 techniques for detecting red blood cell survival(RBCS)detection techniques:red blood cell labeling test and carbon monoxide(CO)breath test.The former has disadvantages such as long measurement times and complicated procedures,while the latter is simple,convenient,moderately priced,and capable of dynamically monitoring changes in RBCS before and after treatment.Currently,the CO breath test is gradually being implemented in clinical practice.RBCS is not only applied to hematologic diseases such as multiple myeloma,myelodysplastic syndromes,lymphoma,and thalassemia,but also to non-hematologic diseases like type 2 diabetes and chronic kidney disease.It can assist in diagnosis,guide treatment,evaluate drug treatment efficacy,and predict disease progression.