Clinical Observation on Regulating the Spine and Unblocking Governor Vessel Acupuncture Combined with Cobamamide Intramuscular Injection in the Treatment of Lumbar Disc Herniation
10.13359/j.cnki.gzxbtcm.2024.11.021
- VernacularTitle:调脊通督针法联合腺苷钴胺肌注治疗腰椎间盘突出症的临床观察
- Author:
Jun-Ren WANG
1
;
Ling-Juan HU
;
Mei LIU
Author Information
1. 北京市和平里医院,北京 100102
- Keywords:
regulating the spine and unblocking governor vessel acupuncture;
Cobamamide;
lumbar disc herniation;
lumbar range of motion;
thromboxane B2;
interleukin 1β;
interleukin 10
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2024;41(11):2961-2967
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy of regulating the spine and unblocking governor vessel acupuncture combined with Cobamamide intramuscular injection in the treatment of lumbar disc herniation(LDH).Methods A total of 124 patients with LDH were randomly divided into observation group and control group,62 cases in each group,and the control group was given conventional treatment combined with Cobamamide intramuscular injection.The observation group was treated with regulating the spine and unblocking governor vessel acupuncture on the basis of the treatment of the control group,and both groups were treated for one month continuously.After one month of treatment,the clinical efficacy of the two groups was evaluated,and the changes of Visual Analogue Scale(VAS)score,Japanese Orthopaedic Association(JOA)score,lumbar Oswestry Disability Index(ODI)score and lumbar range of motion,including Lumbar flexion and extension,rotation,lateral flexion mobility,were observed in the two groups before and after treatment.Serum thromboxane B2(TXB2),interleukin-1β(IL-1β),and interleukin-10(IL-10)levels were compared between the two groups before and after treatment.And the occurrence of adverse reactions in the two groups was evaluated.Results(1)The total effective rate was 91.94%(57/62)in the observation group and 79.03%(49/62)in the control group.The efficacy of the observation group was superior to that of the control group,and the difference was statistically significant(P＜0.05).(2)After treatment,the scores of VAS,JOA and ODI of the patients in the two groups were improved significantly(P＜0.05),and the improvement in the observation group was significantly superior to that in the control group,with a statistically significant difference(P＜0.05).(3)After treatment,the lumbar flexion and extension,rotation and lateral flexion mobility of patients in the two groups were improved significantly(P＜0.05),and the improvement in the observation group was significantly superior to that in the control group,with statistically significant differences(P＜0.05).(4)After treatment,the levels of serum TXB2,IL-1β,and IL-10 of patients in the two groups were significantly improved(P＜0.05),and the improvement in the observation group was significantly superior to that in the control group,with statistically significant differences(P＜0.05).(5)Comparison of the incidence of adverse reactions between the observation group and the control group showed that the difference was not statistically significant(P＞0.05).Conclusion Regulating the spine and unblocking governor vessel acupuncture combined with Cobamamide intramuscular injection in the treatment of LDH can significantly alleviate pain of the patients,improve their lumbar function and range of motion,and promote the expression of serum IL-10 and inhibit the expression of TXB2 and IL-1β,which is safe and effective,and the clinical efficacy is remarkable.
