Exploration on the Essence of Spleen Function and Prospect of Research on Therapeutics and Formulas of Treatment from the Perspective of Spleen
10.13359/j.cnki.gzxbtcm.2024.10.015
- VernacularTitle:脾功能本质与"从脾论治"治法方药研究的探索与展望
- Author:
Nai-Hua LIU
1
;
Chuan-Quan LIN
;
Yong GAO
;
Ya-Fei SHI
;
Meng-Lu ZHU
;
Hua-Feng PAN
Author Information
1. 广州中医药大学,广东广州 510405
- Keywords:
theory of visceral manifestation of spleen;
spleen in charge of transportation and transformation;
spleen qi dispersing the essence;
inflammation-to-tumor transition;
treatment from the perspective of spleen;
strengthening the spleen,dispersing essence an
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2024;41(10):2608-2614
- CountryChina
- Language:Chinese
-
Abstract:
The core of theory of visceral manifestation of spleen is about'spleen in charge of transportation and transformation,spleen qi dispersing the essence'.Middle-jiao spleen-earth has the functions of digesting food and transporting food essence,and maintaining the homeostasis of glucose and lipid metabolism in the body.'Spleen in charge of transportation and transformation,spleen qi dispersing the essence'functions like the glucose and lipid metabolism at physiological state.The deficiency of spleen results in the dysfunction of food in-take and digestion and the susceptibility to external pathogens;qi deficiency and blood stasis lead to the interior damp-heat,and the long-term accumulation of damp-heat develops into stasis and then turns into toxins,which eventually induces inflammation-to-tumor transition.The pathogenesis of'spleen deficiency being the root cause and stasis blended with toxins'is correlated with the pathological changes of inflammation-to-tumor transition.The therapy of strengthening the spleen,dispersing essence and removing turbidity is effective on improving the disorder of glucose and lipid metabolism,and the therapy of strengthening the spleen,resolving stasis and removing toxin is effective on restraining the process of inflammation-to-tumor transition in the stomach.It has become a new direction in the field of spleen-stomach research to expound the scientific connotation of the essence of spleen function of'spleen in charge of transportation and transformation,spleen qi dispersing the essence'from the perspective of glucose and lipid metabolism,to focus on the inflammation-to-tumor transition process of major diseases of digestive system,to explore the evolution of the traditional Chinese medicine syndromes of inflammatory diseases and precancerous lesions of the digestive tract,and to reveal the pharmacological mechanism of treatment from the perspective of spleen,which will enrich the scientific connotation of theory of visceral manifestation of spleen and promote the modernization and internationalization of traditional Chinese medicine.
