Construction and Clinical Application of the Novel Theory of'Stress-Based Breast Cancer Prevention & Treatment'
10.13359/j.cnki.gzxbtcm.2024.10.006
- VernacularTitle:乳腺癌"应激治乳"新理论的构建与临床应用探讨
- Author:
Zhi-Yu WANG
1
;
Yu-Die HU
;
Shi-Cui HONG
;
Shang XU
;
Neng WANG
;
Hong-Lin SITU
;
Yi LIN
Author Information
1. 广东省中医院乳腺病专科医院,广东广州 510120
- Keywords:
breast cancer;
stress-based breast cancer prevention & treatment;
treating breast diseases from the perspective of six stagnations;
regulation of stress homeostasis;
syndrome differentiation and treatment;
clinical prognosis;
traditional Chinese medicine m
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2024;41(10):2547-2554
- CountryChina
- Language:Chinese
-
Abstract:
Stress is a non-specific adaptive response of organisms to internal and external stimuli,which helps maintain the homeostasis of the body's internal environment.However,when the stress response exceeds the body's adaptation threshold,a variety of diseases will be induced.The morbidity and mortality of breast cancer rank the highest among female malignant tumors.Professor LIN Yi,the first master of traditional Chinese medicine(TCM)in the field of breast diseases who founded the theory of'treating breast diseases from the perspective of six stagnations',believes that six stagnations are the core pathogenesis of breast cancer,and six stagnations are closely related to the body's stress response system.TCM has unique advantages in adjusting the balance of stress homeostasis.By reviewing the classical TCM theory,the theory of'treating breast diseases from the perspective of six depressions'and the modern stress theory,this paper put forward the theory of'stress-based breast cancer prevention & treatment',and expounded the pathogenesis features,pathogenic characteristics and molecular mechanism of stress factors in mediating the development and progression of breast cancer.Moreover,the core idea and treatment principle based on the regulation of stress homeostasis were proposed,and the prescription and medication guided by the theory of'stress-based breast cancer prevention & treatment'were summarized.The establishment of the theory of'stress-based breast cancer prevention & treatment'enriches the theoretical system of breast cancer in TCM,and is expected to provide a new approach for improving the clinical prognosis of breast cancer patients.
