Research Progress in the Differentiation and Treatment of Precancerous Lesions of Gastric Cancer with Traditional Chinese Medicine in Recent 10 Years
10.13359/j.cnki.gzxbtcm.2024.08.041
- VernacularTitle:近10年中医辨治胃癌前病变的研究进展
- Author:
Si-Zhong XU
1
;
Jia-Qi LIU
;
Yun-Ran LI
;
Yi ZHAO
Author Information
1. 广州医科大学中西医临床学院,广东广州 511436
- Keywords:
precancerous lesions of gastric cancer(PLGC);
chronic atrophic gastritis;
microscopic syndrome differentiation;
benefiting qi and invigorating spleen;
soothing liver and activating blood;
resolving dampness and eliminating stasis;
resolving stasis and remo
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2024;41(8):2219-2224
- CountryChina
- Language:Chinese
-
Abstract:
This paper reviewed the research progress in the differentiation and treatment of precancerous lesions of gastric cancer(PLGC)with traditional Chinese medicine(TCM)in the recent 10 years.PLGC refers to the intestinal metaplasia and dysplasia of gastric mucosa developed from chronic atrophic gastritis.As an intermediate stage between chronic atrophic gastritis and gastric cancer,PLGC progresses slowly.TCM has certain advantages in the treatment of PLGC.PLGC can be mainly differentiated as five TCM syndrome types:spleen-stomach weakness syndrome,damp-heat in the spleen and stomach syndrome,qi stagnation in the liver and stomach syndrome,stasis obstruction in the stomach collateral syndrome,and stomach-yin deficiency syndrome.The popularization of gastroscopy technology has promoted the development of microscopic syndrome differentiation of gastric diseases.The combination of microscopic syndrome differentiation and macroscopic syndrome differentiation provides more theoretical supports for the TCM syndrome differentiation and treatment of PLGC.The basic pathogenesis of PLGC is due to the weakness of spleen and stomach and the disordered qi movement in the spleen and stomach,complicated by the accumulation of pathological factors such as damp-heat,stasis-toxin,phlegm-damp,and then the stomach-yin will be consumed over time.An amount of clinical studies on the treatment of PLGC with Chinese medicine have been carried out in recent years.The Chinese medicine treatment of PLGC is mainly through benefiting qi and invigorating spleen,assisted by the methods of soothing liver and activating blood,resolving dampness and eliminating stasis,resolving stasis and removing toxins,and nourishing yin and benefiting stomach,so as to prevent the PLGC progressing to gastric cancer.There are few studies on acupuncture treatment of precancerous lesions of gastric cancer.Therefore,it is necessary to carry out more strict and standardized multi-center large-sample RCTs,and to further study the therapeutic mechanism of acupuncture and moxibustion for PLGC,in order to provide more high-level evidence for the treatment of PLGC with TCM therapy.
