Clinical Observation on the Tongyuan Acupuncture Combined with Modified Linggui Zhugan Decoction in the Treatment of Polycystic Ovary Syndrome with Spleen Deficiency and Phlegm-Damp Syndrome
10.13359/j.cnki.gzxbtcm.2024.07.020
- VernacularTitle:通元针法联合加味苓桂术甘汤治疗脾虚痰湿型多囊卵巢综合征的临床观察
- Author:
Luo-Lin ZHOU
1
;
Jun-Liang ZHOU
;
Xing-Ju TAN
;
Yue-Mei LI
;
Dai-Hong LUO
Author Information
1. 广州中医药大学,广东广州 510006
- Keywords:
Tongyuan Acupuncture;
Modified Linggui Zhugan Decoction;
spleen deficiency and phlegm-damp type;
polycystic ovary syndrome(PCOS);
sex hormones;
glucose metablism;
clinical observation
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2024;41(7):1792-1797
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical effect of Tongyuan Acupuncture combined with Modified Linggui Zhugan Decoction in the treatment of polycystic ovary syndrome(PCOS)with spleen deficiency and phlegm-damp syndrome.Methods A total of 86 patients with PCOS of spleen deficiency and phlegm-damp type were randomly divided into observation group and control group,43 cases in each group.The control group was treated with Metformin Hydrochloride Tablets combined with Ethinylestradiol and Cyproterone Acetate Tablets.The observation group was treated with Tongyuan Acupuncture combined with Modified Linggui Zhugan Decoction on the basis of the treatment of the control group.Both groups were treated for three consecutive months.After three months of treatment,the clinical efficacy of the two groups was evaluated.The changes of sex hormone indexes estradiol(E2),testosterone(T),luteinizing hormone(LH),follicle stimulating hormone(FSH)and prolactin(PRL)expression levels were observed before and after treatment in the two groups.The changes of glucose metabolism levels including insulin resistance index(HOMA-IR),fasting insulin(FINS)and fasting blood glucose(FPG)expression levels were compared before and after treatment between the two groups.Results(1)The total effective rate was 90.70%(39/43)in the observation group and 74.42%(32/43)in the control group.The curative effect of the observation group was superior to that of the control group,and the difference was statistically significant(P＜0.05).(2)After treatment,HOMA-IR,FINS and FPG in the two groups were significantly improved(P＜0.05),and the improvement of HOMA-IR,FINS and FPG in the observation group was superior to that in the control group,the difference being significant(P＜0.05).(3)After treatment,the levels of E2,T,LH,FSH and PRL in the two groups were significantly improved(P＜0.05),and the levels of E2,T,LH,FSH and PRL in the observation group were significantly superior to those in the control group,the differences were statistically significant(P＜0.05).Conclusion Tongyuan Acupuncture combined with Modified Linggui Zhugan Decoction in the treatment of spleen deficiency and phlegm-damp type of PCOS can effectively improve the sex hormone level of patients and regulate the glucose metabolism of patients.The clinical effect is significant.
