Curative Effect of Standardized Comprehensive Pure Traditional Chinese Medicine Treatment for Short-Course Sudden Deafness:An Observation of 516 Cases
10.13359/j.cnki.gzxbtcm.2024.07.018
- VernacularTitle:纯中医规范化综合治疗短病程突发性聋516例疗效观察
- Author:
Wen-Zhi LIN
1
;
Peng LIU
;
Wei-Ping HE
;
Hui-Xian XU
;
En-Qin GUO
Author Information
1. 广州中医药大学第一临床医学院,广东广州 510405
- Keywords:
sudden deafness;
short-course;
standardized comprehensive pure traditional Chinese medicine(TCM)treatment;
influencing factors;
type of hearing curve;
degree of deafness;
vertigo;
age
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2024;41(7):1779-1785
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical efficacy of standardized comprehensive pure traditional Chinese medicine(TCM)treatment for short-course sudden deafness and to explore the influencing factors of clinical efficacy.Methods The clinical data of 516 short-course sudden deafness inpatients(TCM group)who were given standardized comprehensive pure TCM treatment were retrospectively analyzed,and their efficacy were compared with the efficacy of 1 024 cases in the Chinese multicenter clinical study of sudden deafness(western medicine group).The analysis was carried out for the influence of the gender,left or right ear,age group,degree of deafness,type of hearing curve,concomitant symptoms(tinnitus,vertigo,and dullness of the ear),and the TCM syndrome types on the efficacy.Results(1)The comparison of baseline data showed that in comparison with the western medicine group,TCM group had relatively low proportion of low-frequency descending type while relatively high proportion of total deafness type,and had relatively high treatment difficulty.The course of treatment in TCM group was shortened by nearly 2/3 in comparison with the western medicine group(12.60 days vs 30 days).(2)Among the 516 patients of the TCM group,175 cases were cured,121 cases were markedly effective,90 cases were effective and 130 cases were ineffective,and the total effective rate was 74.80%.Compared with the 1 024 cases in the western medicine group,there was no significant difference in the overall efficacy or the efficacy evaluated with the hearing curve classification(P>0.05).(3)Analysis of influencing factors of curative effect showed that the type of hearing curve was closely related to the curative effect of sudden deafness(P<0.001).The curative effect of low frequency descent type was the best,and the curative effect of total deafness type was the worst.The cure of deafness was correlated with the degree of deafness,the milder the degree of deafness,the greater the likelihood of recovery(P<0.001).The curative effect of the patients without vertigo was superior to that of the patients with vertigo(P<0.001).The curative effect of adolescent patients was superior to that of middle-aged and elderly patients(P<0.05).There was no correlation between TCM syndrome types and curative effect(P>0.05).Conclusion Standardized comprehensive pure TCM treatment exerts certain curative effect on short-course sudden deafness,and may have some advantages compared with conventional western medicine treatment.The type of hearing curve,degree of deafness,accompanied by vertigo or not,and age group are the influencing factors of the efficacy.