Antimicrobial Resistance of Clinically Important Bacteria Isolated from Hospitals Located in Representative Provinces of Korea.
- Author:
Seong Geun HONG
1
;
Dongeun YONG
;
Kyungwon LEE
;
Eui Chong KIM
;
Wee Kyo LEE
;
Seok Hoon JEONG
;
Won Keun SONG
;
Yeon Jun PARK
;
Mi Na KIM
;
Young UH
;
Jong Hee SHIN
;
Jongwook LEE
;
Ji Young AHN
;
Sun Wha LEE
;
Jae Seok KIM
;
Hee Bong SHIN
Author Information
1. Department of Laboratory Medicine, Colleage of Medicine, Pochon CHA University, Korea.
- Publication Type:Original Article
- Keywords:
MRSA;
VRE;
ESBL;
AmpC -lactamase;
Carbapenemase
- MeSH:
Acinetobacter baumannii;
Ampicillin;
Bacteria*;
Cefotaxime;
Cefoxitin;
Ceftazidime;
Citrobacter freundii;
Cloaca;
Enterobacter cloacae;
Enterococcus faecium;
Escherichia coli;
Haemophilus influenzae;
Health Facility Size;
Imipenem;
Influenza, Human;
Klebsiella pneumoniae;
Korea*;
Methicillin-Resistant Staphylococcus aureus;
Piperacillin;
Pneumonia;
Prevalence;
Pseudomonas aeruginosa;
Serratia marcescens;
Streptococcus pneumoniae;
Vancomycin
- From:Korean Journal of Clinical Microbiology
2003;6(1):29-36
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: A rapid increase of antimicrobial-resistant bacteria has become a serious problem in many countries. The aim of this study was to determine the prevalence of resistance among frequently isolated gram-positive and -negative bacteria in Korea. METHODS: Data of routine antimicrobial susceptibility test for medically important bacteria, isolated during 3 months of 2002, were collected from 12 university and 1 commercial laboratories in Korea. RESULTS: The proportions of methicillin-resistant Staphylococcus aureus (MRSA) were 60-88%, but vancomycin-resistant S. aureus was not detected. Among the Enterococcus faecium isolates, the resistance rate to vancomycin was 29%. The resistance rates of Escherichia coli and Klebsiella pneumoniae: 11% and 24% to cefotaxime, respectively, and 12% and 21% to cefoxitin, respectively. The resistance rates of Citrobacter freundii, Enterobacter cloacae, and Serratia marcescens: 28%, 34% and 21% to cefotaxime, respectively, <1%, 8% and 14% to cefepime, respectively. The resistance rates of Acinetobacter baumannii and Pseudomonas aeruginosa were: 65% and 37% to piperacillin, 64% and 19% to ceftazidime, 13% and 20% to imipenem, respectively. The resistant rates varied according to the hospital size. The resistance rates were generally higher among the isolates in the hospitals with more than 1,000 beds. The rates of penicillin-nonsusceptible Streptococcus pneumoniae were 58-90%. Among the Haemophilus influenzae isolates, 55-68% were resistant to ampicillin. CONCLUSIONS: Antimicrobial resistant strains were prevalent among the medically important clinical isolates, especially, MRSA, vancomycin-resistant enterococci, extended-spectrum -lactamase- or AmpC -lactamase-producing E. coli and K. pneumoniae, third generation cephalosporin-resistant C. freundii, E. cloacae and S. marcescens, imipenem-resistant A. baumannii and P. aeruginosa, penicillin-nonsusceptible S. pneumoniae and ampicillin-resistant H. influenzae. The antimicrobial resistance has become a serious problem in Korea.
