Study on Traditional Chinese Medicine Syndrome Characteristics of Patients with Cervical High-Risk Human Papillomavirus Infection
10.13359/j.cnki.gzxbtcm.2024.07.003
- VernacularTitle:宫颈高危型人乳头瘤病毒感染的中医证候特征研究
- Author:
Qiang WANG
1
;
Jie GUO
;
Dian-Rong SONG
;
Di LU
Author Information
1. 天津中医药大学,天津 301617
- Keywords:
human papillomavirus(HPV)infection;
high-risk human papillomavirus(HR-HPV);
traditional Chinese medicine syndrome characteristics;
syndrome elements;
uterus;
damp-heat stasis stagnation;
liver depression and qi stagnation;
heart-kidney incoordination;
spleen
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2024;41(7):1669-1675
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the characteristics of traditional Chinese medicine(TCM)syndromes in patients with cervical high-risk human papillomavirus(HR-HPV)infection,and to provide reference for clinical syndrome differentiation and treatment of cervical HR-HPV patients.Methods From September 2020 to October 2022,the TCM syndrome manifestations of cervical HR-HPV infection diagnosed by HPV detection in the Gynecology Department of The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine were investigated,and then the distribution of disease-location syndrome elements,disease-nature syndrome elements and syndrome types was analyzed.Results The patients with cervical HR-HPV infection were usually manifested with abnormal vaginal secretions,which accounted for 63.40%.The disease-location syndrome elements of cervical HR-HPV infection were uterus,spleen,liver,kidney,meridians,stomach,heart spirit and heart.Among them,uterus,spleen and liver were most commonly-seen,accounting for 67.00%,58.80%and 55.80%respectively.The disease-nature syndrome elements were dampness,heat,qi stagnation,blood stasis,qi deficiency,yang deficiency,yin deficiency,phlegm and cold.Among them,dampness,heat,qi stagnation and blood stasis were most commonly-seen,accounting for 66.40%,56.60%,36.00%and 31.80%,respectively.In various age groups of the infected patients,the uterus was the predominated disease-location syndrome element,and dampness and heat were the predominated disease-nature syndrome elements.The uterus-spleen was the predominated double disease-location syndrome element,and the uterus-spleen-liver was the predominated triple disease-location syndrome element.Damp-heat was the predominated double disease-nature syndrome element,and damp-heat-blood stasis was the predominated triple disease-nature syndrome element.According to the results of cluster analysis and with reference to the clinical practice,it was found that the main syndrome types of the patients with cervical HR-HPV infection were damp-heat stasis stagnation,liver depression and qi stagnation,heart-kidney incoordination,spleen-stomach yang deficiency.Conclusion In the view of the TCM syndrome,cervical HR-HPV infection is mainly affected with the uterus,and also involves the spleen,liver and kidney.The disease-nature syndrome elements are characterized by dampness and heat,showing the characteristics of deficiency interweaved with excess.The main TCM syndrome types are damp-heat stasis stagnation,liver depression and qi stagnation,heart-kidney incoordination,and spleen-stomach yang deficiency.
