Viral hepatitis E:Clinical manifestations,treatment,and prevention
10.1016/j.livres.2024.01.001
- Author:
Luo QIUMIN
1
;
Chen JIA
;
Zhang YEQIONG
;
Xu WENXIONG
;
Liu YING
;
Xie CHAN
;
Peng LIANG
Author Information
1. Department of Infectious Disease
- Keywords:
Hepatitis E;
Chronic hepatitis;
Screening;
Antiviral therapy;
Vaccination
- From:
Liver Research
2024;8(1):11-21
- CountryChina
- Language:Chinese
-
Abstract:
Hepatitis E is a globally distributed infection that varies in seroprevalence between developed and developing regions.In the less developed regions of Asia and Africa,a high seropositivity rate has been reported for hepatitis E virus(HEV)antibodies.Although acute hepatitis E is often self-limited and has a favorable prognosis,some populations experience severe manifestations,which may progress to liver failure.Moreover,some immunocompromised patients are at risk of developing chronic HEV infection and cirrhosis.Proactive screening,reducing misdiagnosis,improving patient management,timely anti-viral therapy for severe and chronic cases,and vaccination of high-risk groups are important measures to reduce the morbidity of hepatitis E.This review focused on the clinical presentation,management,and prevention of hepatitis E.
