Effect of low-dose aspirin orally on thrombosis prevention in breast cancer patients after PICC catheter
10.3760/j.issn.1674-2907.2014.03.001
- VernacularTitle:小剂量阿司匹林口服对乳腺癌患者PICC置管后血栓预防的影响
- Author:
Baona WANG
1
;
Ying ZAN
;
Li WANG
Author Information
1. 710004 西安交通大学第二附属医院肿瘤科
- Keywords:
Aspirin;
PICC;
Venous thrombosis
- From:
Chinese Journal of Modern Nursing
2014;20(3):249-251
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical effect of aspirin on venous thrombosis in breast cancer patients after peripherally inserted central venous catheter ( PICC ) .Methods Two hundred fifty-sixty breast cancer patients with PICC were divided into the observation group and the control group according the random number table, each with 128 cases. The two groups all received the conventional PICC catheter and maintenance, the observation group received the oral administer of aspirin 100 mg for 28 day, once a day, and the control group did not take any anticoagulation drugs .The venous thrombosis was checked by the clinical observation and color Doppler flow imaging in two groups , and the adverse reactions were also observed in patients.Results The incidence rate of venous thrombosis was 3.1%in the observation group , and was lower than 9.4%in the control group, and the difference was statistically significant (χ2 =3.919, P<0.05).The adverse reactions including obvious allergy , thrombocytopenia and bleeding tendency were not found in the observation group .Conclusions Oral aspirin enteric-coated tablets can effectively prevent venous thrombosis in breast cancer patients after PICC .
