Biliary endoscopy in the management of primary sclerosing cholangitis and its complications
10.1016/j.livres.2019.03.004
- Author:
M.Fung BRIAN
1
;
H.Tabibian JAMES
Author Information
1. University of California Los Angeles-Olive View Internal Medicine Residency Program
- Keywords:
Primary sclerosing cholangitis(PSC);
Biliary tract disease;
Balloon dilation;
Cholangioscopy;
Dominant stricture;
Cholangiocarcinoma(CCA);
Endoscopic retrograde;
cholangiopancreatography(ERCP)
- From:
Liver Research
2019;3(2):106-117
- CountryChina
- Language:Chinese
-
Abstract:
Primary sclerosing cholangitis(PSC)is a chronic,idiopathic,cholestatic liver disease characterized by inflammation and fibrosis of the intrahepatic and/or extrahepatic bile ducts.It can affect individuals of all age groups and gender,has no established pharmacotherapy,and is associated with a variety of neoplastic(e.g.cholangiocarcinoma)and non-neoplastic(e.g.dominant strictures)hepatobiliary com-plications.Given these considerations,endoscopy plays a major role in the care of patients with PSC.In this review,we discuss and provide updates regarding endoscopic considerations in the management of hepatobiliary manifestations and complications of PSC.Where evidence is limited,we suggest pragmatic approaches based on currently available data and expert opinion.
