Research progress in the mechanism of Astragali Radix in the treatment of ischemic stroke
10.3760/cma.j.cn115398-20231125-00296
- VernacularTitle:黄芪治疗缺血性卒中作用机制研究进展
- Author:
Changxin JIN
1
;
Ruobing LI
;
Yaodong GU
;
Xicheng JIANG
Author Information
1. 黑龙江中医药大学基础医学院2022级硕士研究生，哈尔滨 150000
- Keywords:
Astragali Radix (TCD);
Ischemic stroke;
Ischemia reperfusion injury;
Review
- From:
International Journal of Traditional Chinese Medicine
2024;46(12):1677-1681
- CountryChina
- Language:Chinese
-
Abstract:
The active components of Astragali Radix, its patent drugs and preparations can play a protective role on brain tissue through a variety of pharmacological effects such as anti-oxidative stress, inhibition of cell apoptosis, protection of blood-brain barrier, alleviation of inflammatory response, inhibition of ferroptosis, promotion of nerve cell regeneration and new angiogenesis. In the basic research of Astragali Radix in the treatment of ischemic stroke, the repetition rate of experimental indexes is high. The research on upstream levels such as signal pathway and cell type should be strengthened, and the basic research should be effectively connected with clinical research.
