Female with 46, XY karyotype.
10.5468/ogs.2017.60.4.378
- Author:
Eun Jung JUNG
1
;
Do Hwa IM
;
Yong Hee PARK
;
Jung Mi BYUN
;
Young Nam KIM
;
Dae Hoon JEONG
;
Moon Su SUNG
;
Ki Tae KIM
;
Hyo Jung AN
;
Soo Jin JUNG
;
Kyung Bok LEE
Author Information
1. Department of Obstetrics and Gynecology, Inje University Busan Paik Hospital, Busan, Korea. 107526@paik.ac.kr
- Publication Type:Case Report
- Keywords:
46, XY female;
Androgen-insensitivity syndrome;
Gonadal dysgenesis
- MeSH:
46, XY Disorders of Sex Development;
Androgen-Insensitivity Syndrome;
Disorders of Sex Development;
Female*;
Gonadal Dysgenesis;
Gonadal Dysgenesis, 46,XY;
Gonads;
Humans;
Karyotype*;
Male
- From:Obstetrics & Gynecology Science
2017;60(4):378-382
- CountryRepublic of Korea
- Language:English
-
Abstract:
Disorders of sex development (DSD) are congenital conditions characterized by atypical development of chromosomal, gonadal, and phenotypic sex. 46, XY DSD can result from disorders of testicular development or disorders of androgen synthesis/action. Prophylactic gonadectomy should be considered in patients with 46, XY DSD because of the increased risk of gonadal malignancy. We report two rare cases of 46, XY DSD, including XY pure gonadal dysgenesis and complete androgen insensitivity syndrome, who underwent a prophylactic gonadectomy.
