Research progress in the diagnosis and treatment of rheumatoid arthritis with phlegm-dampness syndrome
10.3760/cma.j.cn115398-20231222-00235
- VernacularTitle:类风湿关节炎痰湿证诊疗研究进展
- Author:
Li HAN
1
;
Bin HAN
;
Lin CAO
;
Ming YANG
;
Jianxun REN
Author Information
1. 川北医学院附属医院药剂科，南充 637000
- Keywords:
Arthritis, rheumatoid;
Phlegm-dampness syndrome;
Diagnosis and treatment;
Review
- From:
International Journal of Traditional Chinese Medicine
2024;46(6):808-812
- CountryChina
- Language:Chinese
-
Abstract:
Phlegm-dampness syndrome is a common syndrome type of rheumatoid arthritis (RA), which is closely related to spleen dysfunction. Combined with the understanding of modern medicine on the pathogenesis of phlegm dampness and spleen dysfunction, it is believed that the important factors to promote the development of RA include inflammation related to lipid metabolism disorders, abnormal glucose regulation, and intestinal flora imbalance. Improper diet or external factors lead to glucose and lipid metabolism disorders and affect the imbalance of intestinal microbiota, causing damage to the intestinal mucosal barrier. The metabolites produced promote endogenous glucose and lipid metabolism imbalance and inflammatory response, thus forming the biological basis of RA with phlegm dampness syndrome. The method of invigorating spleen, removing dampness and resolving phlegm can correct the disorder of glucose and lipid metabolism in the body. It can also adjust endogenous glucose and lipid metabolism and inhibit RA inflammation by improving the composition of intestinal flora in RA patients, thus playing a therapeutic role.
