Research progress in the mechanism of acupuncture therapy for vascular cognitive impairment
10.3760/cma.j.cn115398-20230907-00065
- VernacularTitle:针刺治疗血管性认知障碍作用机制研究进展
- Author:
Haiqin WANG
1
;
Ximei XIE
Author Information
1. 陕西中医药大学2022级硕士研究生，咸阳 712046
- Keywords:
Acupuncture;
Vascular cognitive impairment;
Mechanism;
Review
- From:
International Journal of Traditional Chinese Medicine
2024;46(6):813-816,F4
- CountryChina
- Language:Chinese
-
Abstract:
This article has found that acupuncture can treat vascular cognitive impairment (VCI) through alleviating nerve cell apoptosis, enhancing hippocampal synaptic plasticity, improving hippocampal mitochondrial function, reducing brain inflammation, inhibiting oxidative stress response, protecting the blood-brain barrier, promoting angiogenesis, improving cerebral circulation, enhancing default network connectivity in brain regions, and improving white matter damage. At present, it is still in the preliminary stage to explore the mechanism of acupuncture treatment of VCI from the perspective of brain network connection. The existing mechanism researches mostly use electroacupuncture as an intervention method, and the selection of acupoints and the intensity of electroacupuncture stimulation are different. It is necessary to improve the rigor of the experiment, strengthen the study of conventional acupuncture, and explore the operation methods and needle retention time. The existing animal models lack consideration of other complications of VCI, and there are still some differences with the clinical characteristics of VCI patients, which need to be optimized in the future.
