Study on the correlation between the distribution of TCM pathological evidence elements and cardiopulmonary function in hypertension
10.3760/cma.j.cn115398-20230423-00316
- VernacularTitle:高血压病中医病性证素分布与心肺功能相关性研究
- Author:
Xiaoyin CHEN
1
;
Jinhui PANG
;
Mei LENG
;
Jingqian JIANG
;
Jingxiang ZHOU
Author Information
1. 山东中医药大学第一临床医学院2021级硕士研究生，济南 250014
- Keywords:
Essential hypertension;
Pathological evidence;
Cardiopulmonary exercise test;
Root cause analysis
- From:
International Journal of Traditional Chinese Medicine
2024;46(5):575-579
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the correlation of distribution pattern of TCM pathological evidence of hypertension with the related indexes of cardiopulmonary function.Methods:From January 2019 to October 2021, the relevant data of 149 patients with grade 3 hypertension who underwent CPET examination in the Department of Cardiology, Qingdao Hospital of Traditional Chinese Medicine were retrospectively collected, and the pathogenic factors were determined according to the relevant content of "Dialectic of Evidence". The Chi-square test was used to analyze the difference of cardiopulmonary function between the pathological factors, and the Spearman correlation analysis was used to explore the correlation between pathological factors and cardiopulmonary function.Results:The pathogenic factors of 149 hypertensive patients from high to low, are as follows were phlegm, yin deficiency, dampness, yang hyperactivity, blood deficiency, blood stasis, qi deficiency, yang deficiency, qi stagnation, heat, food accumulation, moving wind, pus. There was no statistical significance among the pathological factors ( P>0.05). Spearman correlation analysis showed that Yin deficiency syndrome was negatively correlated with Peak O 2 pulse ( r=-0.213, P=0.009), blood stasis was negatively correlated with Peak VO 2 ( r=-0.170, P=0.039) and Peak O 2 pulse ( r=-0.192, P=0.019), and phlegm syndrome hormone was negatively correlated with anaerobic threshold (AT) ( r=-0.192, P=0.019). Conclusions:TCM pathogenic factors in hypertension mainly focus on phlegm, Yin deficiency, dampness and yang hyperactivity. There is a certain correlation between pathogenic factors and cardiopulmonary function-related indicators, which can provide reference for the clinical treatment of hypertension in TCM.
