Role of tumor cell-derived exosomes in the pre-metastatic niche formation in colorectal cancer
10.3760/cma.j.cn371439-20240429-00109
- VernacularTitle:肿瘤细胞源性外泌体在结直肠癌转移前微环境形成中的作用
- Author:
Jie CHEN
1
;
Hong XU
;
Yutian CHEN
Author Information
1. 苏州大学附属第一医院肿瘤科，苏州 215000
- Keywords:
Exosomes;
Tumor microenvironment;
Colorectal neoplasms;
Neoplasm metastasis;
Pre-metastatic niche
- From:
Journal of International Oncology
2024;51(10):650-654
- CountryChina
- Language:Chinese
-
Abstract:
Distant metastasis is the main cause of death in patients with advanced colorectal cancer, and tumor cell-derived exosomes, as mediators of information transfer, are widely involved in all aspects of pre-metastatic niche formation in colorectal cancer. In-depth study of the mechanism of exosomes in the formation of pre-metastatic niche can provide new ideas for targeted therapy and prediction of tumor progression in colorectal cancer.
