Oral microbiota: a biomarker for the diagnosis and prognosis of oral squamous cell carcinoma
10.3760/cma.j.cn371439-20240304-00086
- VernacularTitle:口腔菌群：口腔鳞状细胞癌诊断和预后的生物标志物
- Author:
Kexin MENG
1
;
Haijun LU
Author Information
1. 青岛大学医学部，青岛 266071
- Keywords:
Oral microbiota;
Oral squamous cell carcinoma;
Biomarkers;
Prognosis
- From:
Journal of International Oncology
2024;51(8):515-519
- CountryChina
- Language:Chinese
-
Abstract:
The oral microbiota has been dynamically changing in the process of formation, development and prognosis of oral squamous cell carcinoma (OSCC), and the two promote and complement each other inseparably. Oral microbiota is different in healthy people, patients with precancerous lesions of OSCC, and patients with OSCC, which means it can be used as a biomarker for the diagnosis of precancerous lesions of OSCC or OSCC. In addition, there are differences in the levels of oral microbiota both at baseline and after treatment among different OSCC patients, which can be used as a prognostic biomarker for OSCC. Furthermore, the modulation of oral microbiota can be used as a microbial therapy to improve the prognosis of OSCC patients by being added to the existing standard therapies.
