Advances in the study of EVI1 in acute myeloid leukemia
10.3760/cma.j.cn371439-20231218-00078
- VernacularTitle:EVI1在急性髓系白血病中的研究进展
- Author:
Shiwei WU
1
;
Kangjia PEI
;
Dongxing ZHANG
;
Zhanyu QIN
;
Shuxia GUO
Author Information
1. 河南中医药大学第五临床医学院（郑州人民医院）血液科，郑州 450000
- Keywords:
Myeloid ecotropic viral integration site 1 protein;
Leukemia, myeloid, acute;
Gene expression;
Therapy
- From:
Journal of International Oncology
2024;51(7):474-477
- CountryChina
- Language:Chinese
-
Abstract:
Acute myeloid leukemia (AML) is a common malignant disease of the hematological system, with high EVI1 expression accounting for 8%-10% of adult AML. Studies have shown that high EVI1 expression plays an important role in the treatment and prognosis of AML. In recent years, researchers have continuously revealed the structure and role of EVI1, but its mechanism of mediating AML has not been fully clarified. Therefore, systematically exploring the role of EVI1 in AML may provide a useful reference for the precise treatment of AML patients with high EVI1 expression.
