Tumor-infiltrating immune cells from a single-cell perspective

VernacularTitle:单细胞视角下的肿瘤浸润免疫细胞
Author: Qilian DU ¹ ; Qinyong HU
Author Information

1. 武汉大学人民医院肿瘤中心，武汉　430060
Keywords: Single-cell analysis; Lymphocytes; Myeloid cells; Neoplasms
From: Journal of International Oncology 2024;51(7):458-463
CountryChina
Language:Chinese
Abstract: Immune microenvironment is closely related to the treatment and prognosis of tumors. Tumor-infiltrating immune cells exhibit significant heterogeneity in different stages of tumors. Single-cell RNA sequencing (scRNA-seq) is widely used in the study of various tumor microenvironment to analyze the biological behavior, mechanisms, and relationship between cells and the body at the single-cell level. The results showed that using scRNA-seq can deeply understand the immune characteristics of tumor-infiltrating immune cells.