Effect of absorption combined with continuous venovenous hemofiltration on eliminating serum inflammatory medium and its nursing
10.3760/cma.j.issn.1674-2907.2013.26.043
- VernacularTitle:全血吸附并联连续性静脉-静脉血液滤过清除血清炎症介质的效果及护理
- Author:
Xi-Qin ZHUANG
1
;
Bin ZHU
;
Liang-Cai DING
;
Da-Ming WANG
;
Li-Ying MIAO
Author Information
1. 苏州大学附属第三医院重症医学科
- Keywords:
Nursing;
Systemic inflammatory response syndrome;
Hemofiltration;
Absorption
- From:
Chinese Journal of Modern Nursing
2013;19(26):3274-3277
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the effect of absorption (AP) combined with continuous venovenous hemofiltration (CVVH) on eliminating serum inflammatory medium for patients with systemic inflammatory response syndrome (SIRS) and its nursing essence.Methods Totals of 63 patients with SIRS were randomly divided into the treatment group (AP combined with CWH,n =31) and the control group (CWH,n =32).Data of serum inflammatory medium,such as TNF,CRP,IL-1,IL-6 and IL-10 were recorded and compared within and between two groups before and after the treatment.Results There was no statistically significant difference in TNF,CRP,IL-1,IL-6 and IL-10 between two groups before treatment (P ＞ 0.05).After the treatment,levels of TNF,CRP,IL-1,IL-6 and IL-10 in 2,26 and 50 hours showed descending tendency in the treatment group,and the differences were statistically significant compared with before (P ＜ 0.05).Levels of TNF,CRP,IL-1,IL-6 and IL-102,26 and 50 hours after the treatment in the control group also showed descending tendency,and the differences were statistically significant compared with before (P ＜ 0.05) except data in 2 hours (P ＞ 0.05).Levels of TNF,CRP,IL-1,IL-6 and IL-10 also had statistically significant differences between two groups at the same time (P ＜ 0.05).For example,score of TNF was respectively (226.4±27.6),(165.3 ±24.5),(120.6 ± 19.2) ng/L 2,26 and 50 hours after treatment in the treatment group and (315.7 ± 38.3),(262.7 ± 29.4),(219.3 ± 25.6) ng/L in the control group,with statistically significant differences (t =-3.31,-7.19,-8.79,respectively; P ＜ 0.05).Condusions AP combined with CVVH can effectively eliminate the serous inflammatory medium for SIRS patients,and close surveillance and nursing are key to smooth treatment and expectations achievement.
