A Case of Cheilitis Granulomatosa.
- Author:
Beom Joon KIM
1
;
Seong Jun SEO
;
Chang Kwun HONG
;
Kye Yong SONG
Author Information
1. Department of Dermatology, Pathology, College of medicine, Chungang University, Seoul, Korea. beomjoon@unitel.co.kr
- Publication Type:Case Report
- Keywords:
Cheilitis granulomatosa;
Corticosteroid
- MeSH:
Adolescent;
Aged;
Biopsy;
Cheilitis*;
Facial Paralysis;
Female;
Gingiva;
Granuloma;
Humans;
Lip;
Melkersson-Rosenthal Syndrome*;
Palate, Hard;
Prednisone;
Tongue;
Turbinates
- From:Korean Journal of Dermatology
2002;40(6):660-665
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cheilitis granulomatosa is a rare disorder of uncertain etiology and characterized by a recurrent orofacial swelling, which was described by Miescher in 1945 for the first time. Symptoms usually manifest during adolescence and initially transient, but subsequently a chronic progressive disability develops. No efficient mode of therapy is yet available. A 71-year-old woman presented with a prominent upper lip swelling which had persisted for more than 6 years. There were no fissuring of the tongue and facial palsy. Oral prednisone was instituted for 6 months with moderate clinical improvement. 2 years later, multiple biopsies were performed at the hard palate, gingiva, and inferior turbinate. And the specimens from the gingiva and inferior turbinate showed scattered non-caseating granulomas, consistent with 'Cheilitis Granulomatosa'. We present here our experience with long-term trial of oral corticosteroid in a 71-year-old woman with cheilitis granulomatosa who had suffered recurrent labial swelling.
