Analysis of risk factors for intraspinal cement leakage in the treatment of osteoporotic vertebral compression fracture by percutaneous vertebroplasty
10.3760/cma.j.cn115396-20240509-00134
- VernacularTitle:骨质疏松性椎体压缩骨折经皮椎体成形术后骨水泥椎管内渗漏的危险因素分析
- Author:
Guofu ZHANG
1
;
Guoying FENG
;
Xueqian CHEN
;
Ya′nan HUANG
Author Information
1. 北京市通州区中西医结合医院骨科，北京 101100
- Keywords:
Spinal fractures;
Vertebroplasty;
Risk factors;
Osteoporosis;
Intraspinal cement leakage
- From:
International Journal of Surgery
2024;51(7):470-475
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the risk factors of intraspinal cement leakage in the treatment of osteoporotic vertebral compression fracture by percutaneous vertebroplasty (PVP).Methods:From January 2018 to December 2021, 156 patients with OVCF who received surgical treatment in Beijing Tongzhou Integrated Traditional Chinese and Western Medicine Hospital were enrolled in this retrospective case-control study. The postoperative CT imaging results were analyzed, and the patients were divided into two groups according to the occurrence of intraspinal cement leakage: leakage group ( n=28) and non-leakage group ( n=128). Measurement data was expressed as mean±standard deviation ( ± s), and t-test was used for comparison of visual analogue score (VAS) between groups; the count data was expressed as the number of cases and percentage (%); univariate and multivariate Logistic regression analysis were used to evaluate the risk factors of postoperative intraspinal cement leakage. Results:All the patients were treated by PVP successfully, without obvious adverse reactions and serious complications occurred during and after the operation. Univariate Logistic regression analysis showed that higher bone mineral density ( P=0.005), OVCF combined with posterior vertebral wall injury ( P<0.001) and higher bone cement dosage ( P=0.013) were the risk factors leading to intraspinal cement leakage. Multivariate Logistic regression analysis showed that higher bone mineral density ( P=0.009, 95% CI: 0.152-0.762, OR=0.340), OVCF combined with posterior vertebral wall injury ( P=0.001, 95% CI: 2.134-15.780, OR=5.803), and higher bone cement dosage ( P=0.005, 95% CI: 1.175-2.505, OR=1.715) were the independent risk factors of intraspinal cement leakage. Conclusion:Intraspinal cement leakage was common complication after PVP. Higher bone mineral density, OVCF combined with posterior vertebral wall injury, and higher bone cement dosage were the independent risk factors affecting intraspinal cement leakage.
