Application of Runxin gingival flusher and Jiyoushen in nasopharyngeal carcinoma with acute oral mucositis
10.3760/cma.j.issn.1674-2907.2013.22.005
- VernacularTitle:润兴牙龈炎冲洗器联合洁悠神在鼻咽癌放射性口腔黏膜炎中的应用
- Author:
Si CHEN
1
;
Jun MIAO
;
Li-Li JIANG
;
Dong-Cheng HE
;
Chang-Hua YU
;
Tao LI
;
Wei-Guo ZHU
Author Information
1. 南京医科大学附属淮安第一医院放疗科
- Keywords:
Nasopharyngeal carcinoma;
Oral mucositis;
Runxin gingival flusher;
Jiyoushen;
Influencing factors
- From:
Chinese Journal of Modern Nursing
2013;19(22):2621-2624
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the efficacy of Runxin gingival flusher and Jiyoushen on nasopharyngeal carcinoma with acute oral mucositis,and analyze its influencing factors.Methods Totals of 92 nasopharyngeal carcinoma patients were randomly divided into study group(n =46) and control group(n =46).The patients of study group were treated with Runxin gingival flusher and Jiyoushen during radiation days,while control group received routine oral nursing.Results In study group,40 patients completed two cycles chemotherapy,while that of 26 patients in control group,and the difference was statistically significant (x2 =10.51,P =0.001).Patients prolonged at least 3 days in study group significantly less than that in control group for acute oral mucositis related to chemotherapy (3 vs 13,x2 =7.57,P =0.006).In study group,40 patients with Ⅰ ～ Ⅱ acute oral mucositis and 6 cases with Ⅲ acute oral mucositis were found,while 23 cases with Ⅰ ～Ⅱ acute oral mucositis and 23 cases with Ⅲ ～ Ⅳ acute oral mucositis in control group,and the difference was statistically significant (x2 =14.06,P ＜ 0.01).Logistic regression analysis found that smoking and male patients related with severe oral mucositis.Conclusions Runxin gingival flusher and Jiyoushen combined for nasopharyngeal carcinoma patients could significantly reduce the incidence of Ⅱ ～ Ⅳ acute oral mucositis,and ensure smoothing of the treatment plans.Smoking related with severe oral mucositis.
