Research progress in the relationship between glutamine and intestinal injury and related mechanisms
10.3760/cma.j.cn115396-20240429-00129
- VernacularTitle:谷氨酰胺与肠道损伤的关系及相关机制的研究进展
- Author:
Yufei LI
1
;
Tingwei ZHAO
;
Wentao LE
;
Feng ZHANG
Author Information
1. 苏州大学附属第三医院(常州市第一人民医院)胃肠外科,常州 213004
- Keywords:
Glutamine;
Enteral nutrition;
Therapeutic uses
- From:
International Journal of Surgery
2024;51(5):354-360
- CountryChina
- Language:Chinese
-
Abstract:
Glutamine (Gln) is the most abundant free amino acids in the body, is the main substrate of intestinal cells. It exerts its repairing effect on intestinal injury through multiple signaling pathways, mainly reflected in maintaining the integrity of intestinal structure, enhancing the function of the intestinal barrier, improving the intestinal ecology, and promoting the absorption of nutrients. Therefore, it is also gradually popularized in the clinical application of intestinal injury. This summarize will summarize the latest research progress on the biological role of Gln, its relationship with intestinal injury, mechanism of action and clinical application.The main purpose of this summarize is intended to explore the research status and development prospects of Gln in the field of intestinal diseases.