Key points and technical difficulties of radical gastrectomy for locally advanced gastric cancer after neoadjuvant therapy
10.3760/cma.j.cn115396-20240511-00141
- VernacularTitle:局部进展期胃癌新辅助治疗后胃癌根治术的要点和难点
- Author:
Yunhe GAO
1
;
Yawen CHEN
;
Peifa LIU
;
Zhi QIAO
Author Information
1. 中国人民解放军总医院第一医学中心普通外科医学部，北京 100853
- Keywords:
Stomach neoplasms;
Postoperative complications;
Neoadjuvant therapy;
Neoadjuvant therapy;
Gastrectomy;
Technical points;
Postoperative complications
- From:
International Journal of Surgery
2024;51(5):289-293
- CountryChina
- Language:Chinese
-
Abstract:
China is a major country for gastric cancer incidence, with the majority being at the advanced stage. Currently, there has been a profound change in the perioperative diagnosis and treatment mode of locally advanced gastric cancer. It has become a gradually recommended diagnostic and treatment process in both eastern and western countries gastric cancer guidelines for patients to undergo radical surgery for gastric cancer after neoadjuvant therapy, followed by postoperative adjuvant therapy. Neoadjuvant therapy can downregulate the tumor grade and clinical stage of gastric cancer, facilitating the successful conduct of radical surgery for gastric cancer. Moreover, it allows for further therapeutic selection based on treatment response and empirically guides adjuvant therapy. However, after neoadjuvant therapy, tumor tissue and the whole body of the patient will inevitably undergo a series of changes, which will affect the implementation process of radical surgery for gastric cancer and postoperative management. Therefore, this article intends to discuss the indications and progress of neoadjuvant therapy for gastric cancer, the timing of radical surgery, technical points, postoperative complications, and other aspects, in order to provide reference and guidance for colleagues in the industry.
