Research progress in mesenchymal stem cell and its secretions for radiation sickness treatment
10.3760/cma.j.cn121382-20240429-00510
- VernacularTitle:间充质干细胞及其分泌物治疗辐射病的研究进展
- Author:
Herui WANG
1
;
Li MIAO
;
Yaoyao CHEN
;
Yongjun LIU
;
Guangyang LIU
Author Information
1. 北京贝来药业有限公司，北京 102629
- Keywords:
Radiation sickness;
Mesenchymal stem cell;
Secretion;
Inflammation;
Tissue regeneration
- From:
International Journal of Biomedical Engineering
2024;47(5):477-484
- CountryChina
- Language:Chinese
-
Abstract:
Mesenchymal stem cell (MSC) has been shown to attenuate injuries in a variety of radiation animal models and has been explored for the treatment of radiation-induced patients, due to its potent immunomodulatory and tissue repair capabilities. Based on its high safety and multiple biological functions, MSC is expected to be used for the treatment of radiation sickness. In this review, the research progress of MSC and its secretions in the treatment of radiation-induced injuries was summarized, such as skin injury, intestinal injury, brain injury, acute radiation syndrome of the hematopoietic system, lung injury, liver injury, and cardiac injury.
