Effect of immunoadsorption treatment on patients with sever systemic lupus erythematosus and its nursing
10.3760/cma.j.issn.1674-2907.2013.20.007
- VernacularTitle:免疫吸附治疗重症系统性红斑狼疮患者的护理
- Author:
Fen-Lian GUO
1
;
Xu CAI
;
Wei-Hong KONG
;
Zhi-Zhong YE
;
Xin-Peng CHEN
;
Zhi-Hua YIN
Author Information
1. 广东医学院附属福田医院香蜜湖风湿病分院风湿科
- Keywords:
Lupus erythematosus,systemic;
Immunoadsorption treatment;
Nursing;
Clinical effect
- From:
Chinese Journal of Modern Nursing
2013;19(20):2380-2382
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect and adverse reactions of immunoadsorption treatment on patients with sever systemic lupus erythematosus (SLE) and discuss related nursing.Methods Seventy-eight severe SLE patients from May 2009 to August 2012 were chosen and randomly divided into the treatment group and the control group.The treatment group was treated with immuno-adsorption combined with hormone and immunosuppressant,while the control group was treated with only hormone immunosuppressant.SLEDAI score and laboratorial indexes were compared between two groups before and after the treatment.Results All indexes were better in the treatment group than in the control group after treatment,with statistically significant difference (P＜0.05).The count of white blood cell and blood sedimentation was respectively(6.4 ±2.3) × 109/L and (20 ± 15) g/L in the treatment group,both higher than (5.1 ± 2.5) x 109/L and (17 ± 2.3) g/L in the control group.Conclusions Strict pre-treatment preparation,proper operation and careful nursing can improve the safety and the tolerability of immunoadsorption treatment.
