Influence of structure design and usage method on performance of insulin pen needles
10.3760/cma.j.cn121382-20240127-00307
- VernacularTitle:结构设计和使用方法对胰岛素笔用针头性能的影响研究
- Author:
Yangzhi LIU
1
;
Lin XIN
;
Shiju YAN
;
Chengli SONG
Author Information
1. 上海理工大学健康科学与工程学院，上海 200093
- Keywords:
Needle;
Insulin pen needle;
Puncture force;
Penetration depth;
Anti-tilt experiment
- From:
International Journal of Biomedical Engineering
2024;47(3):247-254
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the effects of various parameters in the structural design and usage methods of insulin pen needles on their performance.Methods:Twenty-one conventional needles and five self-destructive needles were selected. A testing machine was used to clamp the needle and make it vertically puncture the test material with a constant speed of 50, 100, 150, 200, and 250 mm/min, respectively. The influence of the needle insertion speed on the puncture force was analyzed. The deformation of the needle on the small contact surface and the large contact surface at 4 N was recorded by a Photron high-speed digital camera. The penetration depth at 1 N and 3 N was measured by an indirect measurement and a direct measurement method, respectively, and the maximum damage width of the damage area was recorded. The tilt resistance of the needle at 6°, 9° and 12° under 2 N pressure was obtained by the testing machine. SPSS 27.0 software was used for statistical analysis of the experimental data, and the LSD multiple comparison method was used for one-way analysis of variance.Results:The difference in puncture force between the needle insertion speed of 50 mm/min and the other four needle insertion speeds was statistically significant (all P < 0.05), while the differences between the other groups were not statistically significant (all P > 0.05). The small contact surface needle was significantly deformed, with a large penetration depth, a large maximum damage width, and low anti-tilting resistance. The large contact surface needle was deformed slightly, with a smaller penetration depth, a smaller maximum damage width, and greater resistance to tilting. Conclusions:The influence of the usage method on the large contact surface of the needle is relatively small. The hexagonal and cross-shaped needle seats have stronger anti-tilt ability than the circular needle seat. The hexagonal needle seat is not easy to change with the rotation axis, and the performance is optimal. In the structural design, the size of the connection part should be reduced, and the appropriate shape of the needle base should be selected.
