Multimodal MRI evaluation of vascular cognitive impairment
10.3760/cma.j.issn.1673-4165.2024.08.011
- VernacularTitle:血管性认知损害的多模态MRI评价
- Author:
Yue CHEN
1
;
Hua ZHOU
;
Baoshuai SHAN
;
Yue ZHANG
;
Zhong ZHAO
Author Information
1. 南京医科大学附属苏州医院神经内科，苏州 215000
- Keywords:
Cognition disorders;
Cerebrovascular disorders;
Dementia, vascular;
Magnetic resonance imaging;
Diffusion tensor imaging;
Neurovascular coupling
- From:
International Journal of Cerebrovascular Diseases
2024;32(8):624-630
- CountryChina
- Language:Chinese
-
Abstract:
Vascular cognitive impairment (VCI) refers to a cognitive impairment syndrome caused by cerebrovascular disease and its risk factors, and encompasses a spectrum from mild cognitive impairment to vascular dementia. It is the second leading cause of dementia after Alzheimer's disease (AD). The clinical manifestations of VCI often overlap with neurological diseases such as AD, and its neuropathological changes are heterogeneous, lacking specificity in clinical diagnosis and treatment, thus delaying the optimal timing of treatment. In recent years, with the continuous development of brain structure-function coupling analysis methods based on multimodal MRI, the correlation between brain structure and function has been comprehensively revealed, which is helpful for exploring the pathological and physiological mechanisms of VCI. This article reviews the research progress on the application of multimodal MRI in VCI in recent years, including the study of brain structure function-coupling based on multimodal MRI.
