Impact of non-alcoholic fatty liver disease on the outcome of patients with acute ischemic stroke
10.3760/cma.j.issn.1673-4165.2024.05.003
- VernacularTitle:非酒精性脂肪性肝病对急性缺血性卒中患者转归的影响
- Author:
Xiaorong YU
1
;
Cunsheng WEI
;
Yuan CHEN
;
Tingting YANG
;
Xuemei CHEN
Author Information
1. 南京医科大学附属江宁医院神经内科，南京 211100
- Keywords:
Ischemic stroke;
Non-alcoholic fatty liver disease;
Treatment outcome;
Risk factors
- From:
International Journal of Cerebrovascular Diseases
2024;32(5):333-337
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the impact of non-alcoholic fatty liver disease (NAFLD) on the outcome of patients with acute ischemic stroke (AIS).Methods:Patients with AIS visited the Affiliated Jiangning Hospital of Nanjing Medical University between June 2017 and December 2023 were included retrospectively. At 3 months after onset, the modified Rankin Scale was used to evaluate the outcome, with scores of 0-2 defined as good outcome and >2 defined as poor outcome. Multivariate logistic regression analysis was used to determine the impact of NAFLD on the outcome of patients with AIS. Results:A total of 143 patients with AIS were enrolled, including 95 males (66.43%), aged 67.79±11.15 years. Ninety six patients (67.13%) had good outcome, and 47 (32.87%) had poor outcome. Multivariate logistic regression analysis showed that after adjusting for confounding factors, NAFLD was independently associated with the poor outcome in patients with AIS (odds ratio 2.500, 95% confidence interval 1.015-6.161; P=0.046). Conclusion:NAFLD is an independent risk factor for poor outcome in patients with AIS.
